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Mechanisms and impacts of chromosomal translocations in cancers

Jing H. Wang

Frontiers of Medicine 2012, Volume 6, Issue 3, Pages 263-274 doi: 10.1007/s11684-012-0215-5

Abstract:

Chromosomal aberrations have been associated with cancer development since their discovery more thanChromosomal translocations, a type of particular structural changes involving heterologous chromosomesthe past few decades, tremendous progress has been achieved towards elucidating the mechanism causing chromosomaltranslocations.This review focuses on the basic mechanisms underlying the generation of chromosomal translocations.

Keywords： DNA double strand breaks chromosomal translocations genomic instability spatial proximity carcinogenesis

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Advances in cytogenetic study of spontaneous abortion

Luo Lanrong,Li Jian

Strategic Study of CAE 2015, Volume 17, Issue 6, Pages 65-69

Abstract: Cytogenetic studies of spontaneous abortion are mainly in two aspects,one is embryonic chromosomal abnormalitiesIn spontaneous abortion the embryonic chromosomal abnormal detection rate is around 60 % and this ratioLess structural chromosomal abnormalities of embryo include chromosomal breakage,inversions,deletionsand translocations and so on.traditional chromosome karyotype analysis and fluorescence in situ hybridization techniques (FISH) to chromosomal

Keywords： spontaneous abortion cytogenetics chromosomal abnormalities

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Assessing combined toxic effects of tetracycline and P25 titanium dioxide nanoparticles using

Barsha Roy, Khushboo Kadam, Suresh Palamadai Krishnan, Chandrasekaran Natarajan, Amitava Mukherjee

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 1, doi: 10.1007/s11783-020-1298-x

Abstract: Different chromosomal abnormalities like anaphase bridges, telophase bridges, laggard chromosomes, binucleateThe binary mixture of UVA-TiO2 NPs and TC showed the highest chromosomal aberrations (64.0%±1.26%) than

Keywords： Binary toxicity Cell viability Mitotic index Chromosomal aberration Reactive oxygen species Nanoparticles